Stefan Arnold

Current Project

Total-sample preparation of nanoliter volumes for electron microscopy

Short Biography

Stefan Arnold from Switzerland started his PhD in the Stahlberg group at CINA in April 2013. He studied Nanoscience at the Swiss Nanoscience Institute, University of Basel, Switzerland.

Publications

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Lossless cryo-grid preparation stage for high-resolution electron microscopy

Arnold, S., Braun, T., Stahlberg, H.

US Patent 11,442,074, (2022)

9

Miniaturized sample preparation for transmission electron microscopy

Schmidli, C., Rima, L., Arnold, S., Stohler, T., Syntychaki, A., Bieri, A., Albiez, S., Goldie, K., Chami, M., Stahlberg, H., Braun, T.

Journal of Visual Experiments (JOVE) (137), (2018)

8

Miniaturizing EM Sample Preparation: Opportunities, Challenges and "Visual Proteomics"

Arnold, S., Müller, S., Schmidli, C., Syntychaki, A., Rima, L., Chami, M., Stahlberg, H., Goldie, K., Braun, T.

Proteomics 18(5-6), e1700176 (2018)

PubMed

DOI: DOI

7

Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free electron lasers

Opara, N., Martiel, I., Arnold, S., Braun, T., Stahlberg, H., Makita, M., David, C., Padeste, C.

J. of Applied Crystallography 50, 909-918 (2017)

DOI:

6

Blotting-free and lossless cryo-electron microscopy grid preparation from nanoliter-sized protein samples and single-cell extracts

Arnold, S., Albiez, S., Bieri, A., Syntychaki, A., Adaixo, R., McLeod, R., Goldie, K., Stahlberg, H., Braun, T.

J. Struct. Biol. (197), 220-226 (2017)

PubMed

DOI: 10.1016/j.jsb.2016.11.002

5

Patent: Cryo-electron microscopy from nanoliter sample volumes

Arnold, S., Stahlberg, H., Braun, T.

UniTecTra Technology Opportunity, Ref. No. UA-17/141 (patent application filed), (2016)

4

Total sample conditioning and preparation of nanoliter volumes for electron microscopy

Arnold, S., Albiez, S., Opara, N., Chami, M., Schmidli, C., Bieri, A., Padeste, C., Stahlberg, H., Braun, T.

ACS Nano 10, 4981-4988 (2016)

PubMed

DOI: 10.1021/acsnano.6b01328

3

Single-cell lysis for visual analysis by electron microscopy

Kemmerling, S., Arnold, S., Bircher, B. A., Sauter, N., Escobedo, C., Dernick, G., Hierlemann, A., Stahlberg, H., Braun, T.

J Struct Biol 183(3), 467-73 (2013)

PubMed

2

Connecting micro-fluidics to electron microscopy

Kemmerling, Simon, Ziegler, J., Schweighauser, G., Arnold, S., Giss, D., Müller, S., Ringler, P., Goldie, K., Goedecke, N., Hierlemann, A., Stahlberg, H., Engel, A., Braun, T.

J Struct Biol 177(1), 128-134 (2012)

PubMed

1

2011-2017, Master/PhD Student/PostDoc

+41 61 387 32 23

C-CINA, Biozentrum, Uni Basel, Mattenstrasse 26, Room P36, CH-4058 Basel, Switzerland

stefan.arnold@unibas.ch